Frailty trajectories in community-dwelling older adults during COVID-19 pandemic: The PRESTIGE study.

ABSTRACT:

Background

Frailty has been recognized as potential surrogate of biological age and relevant risk factor for COVID-19 severity. Thus, it is important to explore the frailty trajectories during COVID-19 pandemic and understand how COVID-19 directly and indirectly impacts on frailty condition.

Methods

We enrolled 217 community-dwelling older adults with available information on frailty condition as assessed by multidimensional frailty model both at baseline and at one-year follow-up using Multidimensional Prognostic Index (MPI) tools. Pre-frail/frail subjects were identified at baseline as those with MPI score >0.33 (MPI grades 2-3). Frailty worsening was defined by MPI difference between 12 months follow-up and baseline ≥0.1. Multivariable logistic regression was modelled to

SUBMITTER: Pilotto A 

PROVIDER: S-EPMC9350279 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature