The Association between Smoking and Anal Human Papillomavirus in the HPV Infection in Men Study.

ABSTRACT:

Background

Previous studies show an association between smoking and anal cancer. The objective of this study was to assess the association between smoking and anal HPV (human papillomavirus) prevalence, incidence, and persistence in men.

Methods

The HPV Infection in Men (HIM) Study is a multinational study that enrolled HIV-negative men. At baseline and follow-up visits, anal specimens were collected. HPV genotyping was assessed by linear array. Prevalence ratios (PR) were used to assess the association between smoking and anal HPV prevalence. Odds ratios (OR) were used to assess the association between smoking and anal HPV incidence and ≥12-months persistence.

Results

Current smokers have a higher prevalence [adjusted PR (aPR), 1.36; 95% confidence interval (CI), 1.0

SUBMITTER: Umutoni V 

PROVIDER: S-EPMC9350906 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature