Molecular simulations of the interfacial properties in silk-hydroxyapatite composites.

ABSTRACT: Biomineralization is a common strategy used in Nature to improve the mechanical strength and toughness of biological materials. This strategy, applied in materials like bone or nacre, serves as inspiration for materials scientists and engineers to design new materials for applications in healthcare, soft robotics or the environment. In this regard, composites consisting of silk and hydroxyapatite have been extensively researched for bone regeneration applications, due to their reported cytocompatibility and osteoinduction capacity that supports bone formation in vivo. Thus, it becomes relevant to understand how silk and hydroxyapatite interact at their interface, and how this affects the overall mechanical properties of these composites. This theoretical-experimental work investigat

SUBMITTER: Lopez Barreiro D 

PROVIDER: S-EPMC9351605 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature