Multimodal assessment of sleep in men and women during treatment for opioid use disorder.

ABSTRACT:

Background

Sleep disturbance is common in patients with opioid use disorder (OUD) receiving medication for addiction treatment. Differences between patients on the two primary agonist medications-methadone and buprenorphine-are not well understood.

Methods

In patients receiving either methadone or buprenorphine treatment for OUD, we examined sleep continuity and architecture using ambulatory monitoring to gather both an objective measure (daily sleep EEG; M = 5.76 days, SD = 1.46) and a subjective measure (daily sleep diary; M = 54.10 days, SD = 25.10) of sleep.

Results

Patients treated with buprenorphine versus methadone did not differ on any measure of sleep continuity or architecture. Women had longer EEG-derived total sleep time than men (d = -0.68, 95 % CI -1.32

SUBMITTER: Finan PH 

PROVIDER: S-EPMC9351606 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature