Small vessel vasculitis associated with culture-negative infective endocarditis related to a cardiac device: a case report.

ABSTRACT:

Background

Culture-negative endocarditis is uncommon, occurring in less than a third of all cases of infective endocarditis (IE). Culture-negative IE related to a cardiac device is an even greater diagnostic challenge due to its insidious presentation, with onset of symptoms ranging between 3 and 12 months after device implantation. Sensitivity of the modified Duke's criteria remains low in culture-negative and cardiac device-related IE (CDRIE) since classical signs and symptoms of IE are often absent. Small vessel vasculitis has been reported as an immune response to IE. Recognizing immunological phenomenon related to IE is of paramount clinical importance, prompting the search for an underlying infection and avoiding the use of immunosuppressive medications which would otherwise

SUBMITTER: El-Gaaly M 

PROVIDER: S-EPMC9351725 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature