Neuroplasticity after upper-extremity rehabilitation therapy with sensory stimulation in chronic stroke survivors.

ABSTRACT: This study investigated the effect of using subthreshold vibration as a peripheral sensory stimulation during therapy on cortical activity. Secondary analysis of a pilot triple-blinded randomized controlled trial. Twelve chronic stroke survivors underwent 2-week upper-extremity task-practice therapy. Half received subthreshold vibratory stimulation on their paretic wrist (treatment group) and the other half did not (control). EEG connectivity and event-related de-/resynchronization for the sensorimotor network during hand grip were examined at pre-intervention, post-intervention and follow-up. Statistically significant group by time interactions were observed for both connectivity and event-related spectral perturbation. For the treatment group, connectivity increased at post-intervention

SUBMITTER: Schranz C 

PROVIDER: S-EPMC9351980 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature