Development and validation of an early warning score to identify COVID-19 in the emergency department based on routine laboratory tests: a multicentre case-control study.

ABSTRACT:

Objectives

Identifying patients with a possible SARS-CoV-2 infection in the emergency department (ED) is challenging. Symptoms differ, incidence rates vary and test capacity may be limited. As PCR-testing all ED patients is neither feasible nor effective in most centres, a rapid, objective, low-cost early warning score to triage ED patients for a possible infection is developed.

Design

Case-control study.

Setting

Secondary and tertiary hospitals in the Netherlands.

Participants

The study included patients presenting to the ED with venous blood sampling from July 2019 to July 2020 (n=10 417, 279 SARS-CoV-2-positive). The temporal validation cohort covered the period from July 2020 to October 2021 (n=14 080, 1093 SARS-CoV-2-positive). The external validation coho

SUBMITTER: Boer AK 

PROVIDER: S-EPMC9352566 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature