Risk factors for portal vein thrombosis or venous thromboembolism in a large cohort of hospitalized cirrhotic patients.

ABSTRACT:

Background

Portal vein thrombosis (PVT) and venous thromboembolism (VTE) are fearsome complications of liver cirrhosis.

Objectives

To assess the prevalence and the main risk factors for venous thrombotic complications in hospitalized cirrhotic patients.

Patients/methods

We retrospectively reviewed electronic administrative discharge data of 19461 cirrhotic patients hospitalized over a 35-year period; univariate and multivariate logistic regression was used to asses risk factors for PVT or VTE and their impact on hospital stay and mortality.

Results

382 out of 7445 patients (5.1%) were diagnosed with PVT and 95 (1.3%) with VTE. Liver cirrhosis complications were observed in 45% of patients. Hepatic encephalopathy (HE) (OR 13.88 [10.76-17.98] p < 0.0001), endosco

SUBMITTER: Faccia M 

PROVIDER: S-EPMC9352602 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature