Genetic basis of sudden death after COVID-19 vaccination in Thailand.

ABSTRACT:

Background

Severe acute respiratory syndrome coronavirus 2 vaccination reduces morbidity and mortality associated with coronavirus disease 2019 (COVID-19); unfortunately, it is associated with serious adverse events, including sudden unexplained death (SUD).

Objective

We aimed to study the genetic basis of SUD after COVID-19 vaccination in Thailand.

Methods

From April to December 2021, cases with natural but unexplained death within 7 days of COVID-19 vaccination were enrolled for whole exome sequencing.

Results

Thirteen were recruited, aged between 23 and 72 years; 10 (77%) were men, 12 were Thai; and 1 was Australian. Eight (61%) died after receiving the first dose of vaccine, and 7 (54%) died after receiving ChAdOx1 nCoV-19; however, there were no significan

SUBMITTER: Ittiwut C 

PROVIDER: S-EPMC9352648 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature