An open-source smartphone app for the quantitative evaluation of thin-layer chromatographic analyses in medicine quality screening.

ABSTRACT: Substandard and falsified medicines present a serious threat to public health. Simple, low-cost screening tools are important in the identification of such products in low- and middle-income countries. In the present study, a smartphone-based imaging software was developed for the quantification of thin-layer chromatographic (TLC) analyses. A performance evaluation of this tool in the TLC analysis of 14 active pharmaceutical ingredients according to the procedures of the Global Pharma Health Fund (GPHF) Minilab was carried out, following international guidelines and assessing accuracy, repeatability, intermediate precision, specificity, linearity, range and robustness of the method. Relative standard deviations of 2.79% and 4.46% between individual measurements were observed in the assessm

SUBMITTER: Hauk C 

PROVIDER: S-EPMC9352711 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature