Dose-volume-based evaluation of convolutional neural network-based auto-segmentation of thoracic organs at risk.

ABSTRACT:

Background and purpose

The geometrical accuracy of auto-segmentation using convolutional neural networks (CNNs) has been demonstrated. This study aimed to investigate the dose-volume impact of differences between automatic and manual OARs for locally advanced (LA) and peripherally located early-stage (ES) non-small cell lung cancer (NSCLC).

Material and methods

A single CNN was created for automatic delineation of the heart, lungs, main left and right bronchus, esophagus, spinal cord and trachea using 55/10/40 patients for training/validation/testing. Dice score coefficient (DSC) and 95th percentile Hausdorff distance (HD95) were used for geometrical analysis. A new treatment plan based on the auto-segmented OARs was created for each test patient using 3D for ES-NSCLC (SBRT,

SUBMITTER: Johnston N 

PROVIDER: S-EPMC9352974 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature