Detection rate of fluorine-18 prostate-specific membrane antigen-1007 PET/CT for prostate cancer in primary staging and biochemical recurrence with different serum PSA levels: A systematic review and meta-analysis.

ABSTRACT:

Background

We performed a systematic review and meta-analysis to evaluate the detection rate (DR) of fluoro-prostate-specific membrane antigen (¹⁸F-PSMA-1007) PET/CT in patients with different serum prostate-specific antigen (PSA) levels in the setting of primary staging of prostate cancer (PCa) or biochemically recurring PCa.

Methods

A comprehensive electronic literature search of the PubMed, Embase, and Cochrane Library databases was conducted in accordance with the PRISMA statement. This study was registered in the PROSPERO database (registration number: CRD42022331595). We calculated the DR of ¹⁸F-PSMA-1007 PET/CT in PCa.

Results

The final analysis included 15 studies that described 1,022 patients and 2,034 lesions with ¹⁸F-PSMA-10

SUBMITTER: Liu X 

PROVIDER: S-EPMC9353183 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature