Ca2+ imaging of self and other in medial prefrontal cortex during social dominance interactions in a tube test.

ABSTRACT: The study of social dominance interactions between animals offers a window onto the decision-making involved in establishing dominance hierarchies and an opportunity to examine changes in social behavior observed in certain neurogenetic disorders. Competitive social interactions, such as in the widely used tube test, reflect this decision-making. Previous studies have focused on the different patterns of behavior seen in the dominant and submissive animal, neural correlates of effortful behavior believed to mediate the outcome of such encounters, and interbrain correlations of neural activity. Using a rigorous mutual information criterion, we now report that neural responses recorded with endoscopic calcium imaging in the prelimbic zone of the medial prefrontal cortex show unique correlati

SUBMITTER: Garcia-Font N 

PROVIDER: S-EPMC9353509 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature