Antidepressant effects of a psychedelic experience in a large prospective naturalistic sample.

ABSTRACT:

Background

Over the last two decades, a number of studies have highlighted the potential of psychedelic therapy. However, questions remain to what extend these results translate to naturalistic samples, and how contextual factors and the acute psychedelic experience relate to improvements in affective symptoms following psychedelic experiences outside labs/clinics. The present study sought to address this knowledge gap.

Aim

Here, we aimed to investigate changes in anxiety and depression scores before versus after psychedelic experiences in naturalistic contexts, and how various pharmacological, extrapharmacological and experience factors related to outcomes.

Method

Individuals who planned to undergo a psychedelic experience were enrolled in this online survey study. D

SUBMITTER: Nygart VA 

PROVIDER: S-EPMC9353970 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature