Evaluation of the nicotine metabolite ratio in smoking patients treated with varenicline and bupropion.

ABSTRACT: Background: Smoking is the leading cause of preventable death worldwide. It is responsible for several types of cancer, cardiovascular diseases, and diseases of the reproductive system, among others. Therefore, advances in research are increasingly necessary in order to make smoking cessation treatment more effective. Some studies have investigated the association of the nicotine metabolite ratio (NMR) with general characteristics and treatment outcomes. In the present study, the main aim was to evaluate the NMR in smoking patients from an Assistance Program of a tertiary cardiology hospital. Methodology: Serum samples were collected from 185 patients at T0 (while patients were still smoking and before starting pharmacological treatment). Cotinine and hydroxycotinine analytes

SUBMITTER: Tomaz PRX 

PROVIDER: S-EPMC9354088 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature