Medication use and risk of amyotrophic lateral sclerosis-a systematic review.

ABSTRACT:

Background

Studying whether medications act as potential risk factors for amyotrophic lateral sclerosis (ALS) can contribute to the understanding of disease etiology as well as the identification of novel therapeutic targets. Therefore, we conducted a systematic review to summarize the existing evidence on the association between medication use and the subsequent ALS risk.

Methods

A systematic review was conducted in Medline, Embase, and Web of Science from the date of database establishment to December 10, 2021. References of identified articles were further searched for additional relevant articles. Studies were included if (1) published in English, (2) explored medication use as exposure and development of ALS as outcome, and (3) the design was a human observational study

SUBMITTER: Cui C 

PROVIDER: S-EPMC9354307 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature