The incidence of TB and MDR-TB in pediatrics and therapeutic options: a systematic review.

ABSTRACT:

Background

Tuberculosis (TB) is considered one of the top 10 causes of death worldwide and the leading cause of death from a single infectious agent. Multidrug-resistant (MDR) TB can affect people of all age groups, including children (aged 0-15 years). However, very little is known about the extent of this problem in children. This systematic review aims to investigate the incidence of TB and drug-resistant (DR) TB among the pediatric population. It also reviews the therapeutic options available to treat the condition.

Methods

A comprehensive search for all relevant evidence was conducted. The following databases were searched: MEDLINE, CINAHL, and Web of Science. The searched time frame was limited from January 1990 to December 2020 with a focus on the incidence of TB and

SUBMITTER: Harichander S 

PROVIDER: S-EPMC9354367 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature