Abdominal massage alleviates functional diarrhea in immature rats via modulation of intestinal microbiota and tight junction protein.

ABSTRACT: Functional diarrhea (FD) is a common type of chronic diarrhea in children. Recurrent diarrhea can negatively impact children's quality of life and raise healthcare costs significantly. However, conventional treatments are ineffective and limited. Moreover, children with chronic conditions have poor medication compliance. Therefore, non-pharmacological and complementary treatments are urgently needed. In China, abdominal massage is widely used to treat diarrhea in children. Numerous clinical studies have verified its usefulness in treating gastrointestinal disorders as well. Nevertheless, its intrinsic mechanisms are still unclear, and the impact of massage direction on treatment effects has received less attention. In our study, we found that FD was not associated with pathogen infection.

SUBMITTER: Huang Y 

PROVIDER: S-EPMC9354804 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature