A pilot investigation of the tricuspid valve annulus in newborns with hypoplastic left heart syndrome.

ABSTRACT:

Objective

Hypoplastic left heart syndrome (HLHS) is a congenital disease characterized by an underdevelopment of the anatomical components inside the left heart. Approximately 30% of HLHS newborns will develop tricuspid regurgitation (TR), and it is currently unknown how the valve annulus mechanics and geometry are associated with regurgitation. Thus, we present an engineering mechanics-based analysis approach to quantify the mechanics and geometry of the HLHS-afflicted tricuspid valve (TV), using 4-dimensional echocardiograms.

Methods

Infants born with hypoplastic left heart syndrome (n=8) and healthy newborns (n=4) had their tricuspid valves imaged, and the data was imported to the 3D Slicer. The annular curves were defined at five points in the cardiac cycle

SUBMITTER: Ross CJ 

PROVIDER: S-EPMC9354836 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature