A systematic review: Molecular docking simulation of small molecules as anticancer non-small cell lung carcinoma drug candidates.

ABSTRACT: Non-small cell lung carcinoma (NSCLC) is a type of lung cancer with the highest prevalence and mortality rate worldwide. Many cases of this type of cancer are overexpression on epidermal growth factor receptor (EGFR). The use of currently available EGFR inhibitors as one of the treatment options for NSCLC still shows various shortcomings, especially the high failure rate of therapy due to resistance. It is important to find NSCLC drug candidates with EGFR inhibitory activity. There are various published articles and it is prominent to draw evidence-based scientific conclusions as a basis of decision-making to select potential compounds for further research. Polymer matrix composites and ScienceDirect are used as a database for article screening. Research using molecular docking method targ

SUBMITTER: Hidayat S 

PROVIDER: S-EPMC9355054 | biostudies-literature | 2022 Jul-Sep

REPOSITORIES: biostudies-literature