Metasurface-based bijective illumination collection imaging provides high-resolution tomography in three dimensions.
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ABSTRACT: Microscopic imaging in three dimensions enables numerous biological and clinical applications. However, high-resolution optical imaging preserved in a relatively large depth range is hampered by the rapid spread of tightly confined light due to diffraction. Here, we show that a particular disposition of light illumination and collection paths liberates optical imaging from the restrictions imposed by diffraction. This arrangement, realized by metasurfaces, decouples lateral resolution from depth-of-focus by establishing a one-to-one correspondence (bijection) along a focal line between the incident and collected light. Implementing this approach in optical coherence tomography, we demonstrate tissue imaging at 1.3 μm wavelength with ~ 3.2 μm lateral resolution, maintained nearly intact ove
SUBMITTER: Pahlevaninezhad M
PROVIDER: S-EPMC9355264 | biostudies-literature | 2022 Mar
REPOSITORIES: biostudies-literature
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