Early Developmental Trajectories in Infants With Neurofibromatosis 1.

ABSTRACT:

Objective

To examine the trajectories of cognitive, motor and behavioural development in infants with NF1 compared to infants without a family history of neurodevelopmental difficulties.

Study design

Infants with NF1 and low-risk controls were recruited from 5 months of age and followed longitudinally. Data from standardised tests was gathered at 5, 10 and 14 months and developmental trajectories of motor, language, behaviour, sleep, social development and parent-infant interaction were examined. Linear mixed modelling was used to estimate group differences in cognitive and behavioural measures over time.

Results

No group differences were observed on Mullen Scale of Early Learning, overall adaptive functioning, temperament or behavioural measures. There were no group

SUBMITTER: Garg S 

PROVIDER: S-EPMC9355323 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature