Perioperative Hemodynamic Optimization in Patients at Risk for Delirium - A Randomized-Controlled Trial.

ABSTRACT:

Background

Post-operative delirium is common in elderly patients and associated with increased morbidity and mortality. We evaluated in this pilot study whether a perioperative goal-directed hemodynamic optimization algorithm improves cerebral oxygenation and can reduce the incidence of delirium.

Materials and methods

Patients older than 70 years with high risk for post-operative delirium undergoing elective non-cardiac surgery were randomized to an intervention or control group. Patients in the intervention group received a perioperative hemodynamic optimization protocol based on uncalibrated pulse-contour analysis. Patients in the control group were managed according to usual standard of care. Incidence of delirium until day seven was assessed with confusion assessment met

SUBMITTER: Fuest KE 

PROVIDER: S-EPMC9355693 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature