Predicting the benefit of stereotactic body radiotherapy of colorectal cancer metastases

ABSTRACT: Highlights • Predicting the benefit from Stereotactic body radiotherapy (SBRT) of colorectal cancer metastases.• CLInical Categorical Algorithm (CLICAL©) – a predictive algorithm applied to SBRT.• The benefit from SBRT varies among patients with metastatic colorectal cancer.• CLICAL© may be used as a screening tool for SBRT referrals.

Aim

To evaluate Stereotactic body radiotherapy (SBRT) in metastatic colorectal cancer (mCRC) and identify the benefit of the treatment by using a predictive algorithm.

Methods

85 patients treated with SBRT for mCRC were retrospectively analyzed. The CLInical Categorical Algorithm (CLICAL©) was used to predict probability of relapse after SBRT. Variables pre-SBRT were tested for significance for time to relapse (TTR). The patients’ CLICAL© sc

SUBMITTER: Lindberg S 

PROVIDER: S-EPMC9356237 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature