Neural correlates of repetitive negative thinking: Dimensional evidence across the psychopathological continuum.

ABSTRACT: Repetitive negative thinking (RNT) captures an important transdiagnostic factor that predisposes to a maladaptive stress response and contributes to diverse psychiatric disorders. Although RNT can best be seen as a continuous symptom dimension that cuts across boundaries from health to various psychiatric disorders, the neural mechanisms underlying RNT have almost exclusively been studied in health and stress-related disorders, such as depression and anxiety disorders. We set out to study RNT from a large-scale brain network perspective in a diverse population consisting of healthy subjects and patients with a broader range of psychiatric disorders. We studied 46 healthy subjects along with 153 patients with a stress-related and/or neurodevelopmental disorder. We focused on three networks,

SUBMITTER: van Oort J 

PROVIDER: S-EPMC9356323 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature