Time-varying intensity of oxygen exposure is associated with mortality in critically ill patients with mechanical ventilation.

ABSTRACT:

Background

There is no consensus exists regarding the association between oxygen exposure (arterial oxygen tension or fraction of inspired oxygen) and outcomes for patients with mechanical ventilation. Additionally, whether the association remains persistent over time is unknown. We aimed to explore the association between exposure to different intensities of oxygen exposure over time and 28-day mortality in patients with mechanical ventilation.

Methods

We obtained data from the Medical Information Mart for Intensive Care IV (MIMIC-IV), which included adult (≥ 18 years) patients who received invasive mechanical ventilation for at least 48 h. We excluded patients who received extracorporeal membrane oxygenation (ECMO) or who initiated ventilation more than 24 h after ICU admi

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC9356484 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature