Significance of levothyroxine treatment on serum lipid in pregnant women with subclinical hypothyroidism.

ABSTRACT:

Background

There is no consensus reference range for serum lipid levels during pregnancy. The benefit of levothyroxine (L-T4) on serum lipid levels are unclear among pregnant women with subclinical hypothyroidism (SCH).

Objective

To determine the recommended reference ranges for serum lipid concentrations during pregnancy and effects of L-T4 treatment on serum lipids in pregnant women with SCH.

Design

Cohort study.

Methods

A analysis of 20,365 women in the first trimester was conducted at Beijing Obstetrics and Gynecology Hospital, Capital Medical University during 2018-2020. After excluding women with adverse pregnancy outcomes, we determined the reference range of serum lipid in the first and third trimesters of pregnancy by using median and quartile to deter

SUBMITTER: Yang Y 

PROVIDER: S-EPMC9356505 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature