Polypharmacy and trajectories of health-related quality of life in older adults: an Australian cohort study.

ABSTRACT:

Background

Health-related quality of life (HRQoL) is an important outcome measure when considering medical treatment; however, the impact of polypharmacy on trajectories of HRQoL over time is unknown. This study aimed to investigate the association between polypharmacy status and trajectories of HRQoL in older adults.

Methods

A longitudinal cohort study of 2181 community-dwelling adults, 65 years and older, who participated in the 2013 to 2017 waves of the Household Income and Labour Dynamics in Australia (HILDA) Survey. Polypharmacy was defined as the regular use of ≥ 5 prescription medications. Polypharmacy status was categorised into no polypharmacy, in 2013 only (baseline only polypharmacy), in 2017 only (incident polypharmacy) or at both time points (persistent polyphar

SUBMITTER: Aljeaidi MS 

PROVIDER: S-EPMC9356923 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature