Artificial neural network for cytocompatibility and antibacterial enhancement induced by femtosecond laser micro/nano structures.

ABSTRACT: The failure of orthopedic and dental implants is mainly caused by biomaterial-associated infections and poor osseointegration. Surface modification of biomedical materials plays a significant role in enhancing osseointegration and anti-bacterial infection. In this work, a non-linear relationship between the micro/nano surface structures and the femtosecond laser processing parameters was successfully established based on an artificial neural network. Then a controllable functional surface with silver nanoparticles (AgNPs) to was produced to improve the cytocompatibility and antibacterial properties of biomedical titanium alloy. The surface topography, wettability, and Ag⁺ release were carefully investigated. The effects of these characteristics on antibacterial activity and cyto

SUBMITTER: Lu L 

PROVIDER: S-EPMC9357338 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature