Investigating sex differences in acute intoxication and verbal memory errors after ad libitum cannabis concentrate use.

ABSTRACT:

Background

An innovative naturalistic at-home administration procedure was used to investigate sex differences in subjective drug effects and verbal memory errors after ad libitum use of high potency state legal market Δ9-tetrahydrocannabinol (THC) concentrate.

Methods

Regular concentrate users were randomly assigned to ad libitum administration of one of two cannabis concentrate products (70 % or 90 % THC) that they purchased from a dispensary. 65 participants (N = 34 men, N = 31 women) were assessed in a mobile pharmacology lab before, immediately after, and 1 -h after ad libitum concentrate use. Plasma cannabinoids (THC, 11-OH-THC, CBD), subjective drug effects, and verbal memory errors were assessed at all three time points.

Results

Although men and women exhibite

SUBMITTER: Gibson LP 

PROVIDER: S-EPMC9357512 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature