Relationship of Retinal Vessel Caliber with Age-Related Macular Degeneration.

ABSTRACT:

Purpose

Evaluate the relationship between retinal vascular caliber and age-related macular degeneration (AMD) severity or progression.

Methods

A retrospective secondary analysis of 1172 fundus photographs and clinical data from the prospective Age-Related Eye Disease Study (AREDS). Central retinal artery equivalent (CRAE), central retinal vein equivalent (CRVE), and arteriole-to-venule ratio (AVR) were measured using the Parr-Hubbard-Knudtson formula. Univariate and multivariate regressions were used to determine the association of CRAE, CRVE, and AVR with age, sex, smoking status, presence of cilioretinal artery, and AMD severity at baseline and 5 years using the 9-step AMD severity score.

Results

Only CRAE and CRVE were higher in men (P < 0.001), current smok

SUBMITTER: Toulouie S 

PROVIDER: S-EPMC9357695 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature