Reduced childhood social attention in autism model marmosets predicts impaired social skills and inflexible behavior in adulthood.

ABSTRACT: Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social and communication impairments and restricted and repetitive behavior. Although there is currently no established cure for ASD, early interventions for deficits of attention to other individuals are expected to reduce the progression of ASD symptoms in later life. To confirm this hypothesis and improve early therapeutic interventions, it is desirable to develop an animal model of ASD in which social attention is impaired in childhood and ASD-like social behavior is observed in adulthood. However, rodent models of ASD have difficulty in recapitulating the deficit of gaze-based social attention. In this study, we examined the direction of gaze toward other conspecifics during childhood and puberty in a th

SUBMITTER: Nakagami A 

PROVIDER: S-EPMC9357878 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature