Efficacy and safety of Puerarin injection on acute heart failure: A systematic review and meta-analysis.

ABSTRACT:

Objective

This study aimed to assess the adjunctive efficacy and safety of Puerarin injection (PI) on acute heart failure (AHF) based on a systematic review and meta-analysis.

Methods

Nine databases were searched from March 1990 to March 2022 to identify randomized controlled trials (RCTs) related to the adjunctive treatment of PI for AHF. The Cochrane collaboration tool was used to assess the risk of bias in the included studies. Meta-analysis and subgroup and sensitivity analyses were conducted by RevMan 5.3 software. The evidence's certainty was evaluated by grading recommendations assessment, development, and evaluation (GRADE) methods.

Results

A total of 8 studies were included with a total of 614 patients with AHF. The meta-analysis demonstrated that adjunctive

SUBMITTER: Li Z 

PROVIDER: S-EPMC9357890 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature