Fabrication of "electroactive cells" using bio-inspired polydopamine-derived carbon nanoparticles for manipulation of cells with electrical stimulation.

ABSTRACT: In this study, we report some bio-inspired carbon nanoparticles (CNPs) that exhibit high fluorescence quantum yields, good conductivity, excellent dispersion in aqueous solution, high cell-uptake efficiency, and no cytotoxicity as well. We were inspired by mussels' adhesive components to synthesize polydopamine nanoparticles and then use a carbonization process to prepare fluorescent CNPs. Using some surfactants, we could control the sizes of CNPs and increase their dispersion in water. Fluorescence spectroscopy confirmed the excitation of CNPs at 360 nm and emission of blue light with a 400-450 nm wavelength. High quantum yields of greater than 20% were also measured. Transmission electron microscopy proved that the addition of surfactants could shrink particles to several nanometers in s

SUBMITTER: Li FY 

PROVIDER: S-EPMC9358047 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature