Reclassifications of ischemic stroke patterns due to variants of the Circle of Willis.

ABSTRACT:

Background

Variants of the Circle of Willis (vCoW) may impede correct identification of ischemic lesion patterns and stroke etiology. We assessed reclassifications of ischemic lesion patterns due to vCoW.

Methods

We analyzed vCoW in patients with acute ischemic stroke from the 1000+ study using time-of-flight magnetic resonance angiography (TOF MRA) of intracranial arteries. We assessed A1 segment agenesis or hypoplasia in the anterior circulation and fetal posterior cerebral artery in the posterior circulation. Stroke patterns were classified as one or more-than-one territory stroke pattern. We examined associations between vCoW and stroke patterns and the frequency of reclassifications of stroke patterns due to vCoW.

Results

Of 1000 patients, 991 had evaluable magne

SUBMITTER: Rangus I 

PROVIDER: S-EPMC9358303 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature