Focal therapy for prostate cancer: what is really needed to move from investigational to valid therapeutic alternative?-a narrative review.

ABSTRACT:

Background and objective

The most widely accepted therapeutic alternatives for men with intermediate risk prostate cancer (PCa) are mainly represented by whole gland therapies such as surgery or radiotherapy. However, these treatments can carry in some cases profound functional side effects. With the improvement of risk assessment tools and imaging modalities, in particular with the introduction of multiparametric magnetic resonance imaging of the prostate, a fine topographic characterisation of PCa lesions within the prostatic gland is now possible. This has allowed the development of gland-sparing therapies such as focal therapy (FT) as a means to provide an even more tailored approach in order to safely reduce, where feasible, the harms carried by whole gland therapies. Unfortun

SUBMITTER: Pellegrino A 

PROVIDER: S-EPMC9358522 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature