Phenol-soluble modulin contributes to the dispersal of Staphylococcus epidermidis isolates from catheters.

ABSTRACT: Staphylococcus epidermidis (S. epidermidis), a human commensal, has been implicated in invasive infection in humans due to their ability to form biofilm. It is assumed that when a biofilm is dispersed it will subsequently cause a more severe infection. The clinical significance of S. epidermidis isolated from sterile body fluid (BF) remains unclear, and might be related to dispersal from catheter-associated biofilm infection. To evaluate this relationship, we evaluated S. epidermidis isolates from catheters (CA) or BF in hospitalized patients. Sequence type 2 (ST2) is the most prevalent type isolated from infection sites. Although the specific STs were also observed in isolates from different sites, we observed that the main sequence type was ST2, followed by ST59, amo

SUBMITTER: Jin Y 

PROVIDER: S-EPMC9358717 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature