Relationships between adiposity distribution and metabolic health in preconception women in South Africa.

ABSTRACT:

Objective

Adipose tissue is a central regulator of metabolic health and a contributor to systemic inflammation. Patterns of adiposity deposition are important to understand for optimizing health. This study aimed to asses relationships between adiposity deposition and metabolic and inflammatory biomarkers in South African women prior to conception.

Methods

Non-pregnant, healthy women (n = 298) were recruited for this cross-sectional study via home visits. Body composition was measured by Dual X-ray Absorptiometry. Inflammation markers C-reactive protein (CRP), alpha1-acid glycoprotein (AGP), hemoglobin A1c (HbA1c), and blood pressure were scored according to risk. A summative metabolic health risk score was created for women with obesity. Generalized regression models

SUBMITTER: Prioreschi A 

PROVIDER: S-EPMC9358758 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature