Sex- and body mass index-specific reference intervals for serum leptin: a population based study in China.

ABSTRACT:

Background

Leptin is a peptide hormone secreted by adipose tissue and is an important determinant of obesity and its complications. The purpose of this study was to establish sex- and body mass index (BMI)-specific reference intervals for serum leptin in a Chinese population and investigate the factors influencing leptin concentrations.

Methods

Fasting serum leptin levels were assayed in 469 men and 773 women from randomly sampled Chinese residents. Blood glucose, insulin, hemoglobin A1c (HbA1c), liver enzymes, blood lipid profiles, creatinine, and uric acid (UA) levels were measured. Pearson's correlation coefficient and multiple linear regression analyses were used to estimate the relationship between serum leptin level and other variables. The reference intervals were det

SUBMITTER: Cheng J 

PROVIDER: S-EPMC9358897 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature