The association between early formula and reduced risk of cow's milk allergy during the first three year of life: a Japanese cohort study.

ABSTRACT:

Background

Our recent observational study showed that regular consumption of cow's milk (CM) formula during early infancy (3-6 months old) was associated with a reduced risk of CM allergy (CMA) at 12 months old. However, the long-term association is unclear. The present study was aimed to examine how long this inverse association persists after 12 months old.

Methods

This study used the dataset of an ongoing nationwide prospective cohort, the Japan Environment and Children's Study, in which participants were registered between January 2011 and March 2014. We analyzed 65,568 children followed-up until 36 months old. The exposure factors were the consumption statuses of formula milk from 0-3, 3-6, and 6-12 months old. The primary outcome was the prevalence of CMA at 6, 12, 18,

SUBMITTER: Ikari K 

PROVIDER: S-EPMC9358901 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature