Bioprosthesis in aortic valve replacement: long-term inflammatory response and functionality.

ABSTRACT:

Background

The evaluation of long-term inflammatory response and function in postoperative patients with aortic valve replacement (AVR) deserves special analysis because it is important to try to prevent reoperation and improve durability and functionality of the prostheses. It is our objective METHODS: In this study, we included a cohort of patients with aortic valve damage treated by AVR with mechanical prosthesis, bio prosthesis and we included a control group.

Results

We found that IL-4 and osteopontin levels were higher in patients with mechanical vs biological prostheses (p=0.01 and p=0.04, respectively), osteoprotegerin (OPG) levels were decreased (p=0.01), women had lower levels of ET-1 and IL-6, (p=0.02) (p=0.04), respectively. Patients older than 60 years had decre

SUBMITTER: Saucedo-Orozco H 

PROVIDER: S-EPMC9358956 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature