The neurobiology of misophonia and implications for novel, neuroscience-driven interventions.

ABSTRACT: Decreased tolerance in response to specific every-day sounds (misophonia) is a serious, debilitating disorder that is gaining rapid recognition within the mental health community. Emerging research findings suggest that misophonia may have a unique neural signature. Specifically, when examining responses to misophonic trigger sounds, differences emerge at a physiological and neural level from potentially overlapping psychopathologies. While these findings are preliminary and in need of replication, they support the hypothesis that misophonia is a unique disorder. In this theoretical paper, we begin by reviewing the candidate networks that may be at play in this complex disorder (e.g., regulatory, sensory, and auditory). We then summarize current neuroimaging findings in misophonia and pres

SUBMITTER: Neacsiu AD 

PROVIDER: S-EPMC9359080 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature