A 3-D virtual human model for simulating heat and cold stress.

ABSTRACT: In this study, we extended our previously developed anatomically detailed three-dimensional (3-D) thermoregulatory virtual human model for predicting heat stress to allow for predictions of heat and cold stress in one unified model. Starting with the modified Pennes bioheat transfer equation to estimate the spatiotemporal temperature distribution within the body as the underlying modeling structure, we developed a new formulation to characterize the spatial variation of blood temperature between body elements and within the limbs. We also implemented the means to represent heat generated from shivering and skin blood flow that apply to air exposure and water immersion. Then, we performed simulations and validated the model predictions with experimental data from nine studies, representing

SUBMITTER: Gulati T 

PROVIDER: S-EPMC9359647 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature