Printed Ultrastable Bioplasmonic Microarrays for Point-of-Need Biosensing.

ABSTRACT: Paper-based point-of-need (PON) biosensors are attractive for various applications, including food safety, agriculture, disease diagnosis, and drug screening, owing to their low cost and ease of use. However, existing paper-based biosensors mainly rely on biolabels, colorimetric reagents, and biorecognition elements and exhibit limited stability under harsh environments. Here, we report a label-free paper-based biosensor composed of bioplasmonic microarrays for sensitive detection and quantification of protein targets in small volumes of biofluids. Bioplasmonic microarrays were printed using an ultrastable bioplasmonic ink, rendering the PON sensors excellent thermal, chemical, and biological stability for their reliable performance in resource-limited settings. We fabricated silicone hydr

SUBMITTER: Guo H 

PROVIDER: S-EPMC9359782 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature