Lack of full sequencing GBA1 studies for patients with Parkinson's disease in Latin America.

ABSTRACT: Full sequencing of the GBA1 gene in patients with Parkinson's disease provides a wide screening of pathogenic variants, but less developed regions of the world, like Latin America, may have difficulties in performing full sequencing. We performed a systematic review with meta-analysis to explore the prevalence and the odds ratio of specific GBA1 variants in Parkinson's disease in Latin America. We noted a lack of full sequencing GBA1 studies in Latin America.

SUBMITTER: Santos-Lobato BL 

PROVIDER: S-EPMC9360049 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature