Influenza vaccination and mortality among adults with heart failure in an integrated healthcare delivery system, 2009-2018.

ABSTRACT:

Background

Influenza infection can result in decompensation or exacerbation of heart failure (HF) symptoms, hospitalization, and death.

Objective

To examine the association of influenza vaccination with mortality and hospitalization during influenza and non-influenza seasons between 2009 and 2018.

Design, setting, and participants

In this prospective, observational cohort study, we included Kaiser Permanente Southern California members with a HF diagnosis prior to September 1 each year from 2009 to 2017.

Exposure

The first influenza vaccination in each season (September 1 to May 31) was recorded. Vaccinated/unvaccinated patients were matched 1:1 on age, sex, and ejection fraction at the vaccination date (n-total = 74,870).

Main outcomes

Patients were fol

SUBMITTER: Mefford MT 

PROVIDER: S-EPMC9360203 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature