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Relationship Between Cumulative Adverse Childhood Experiences and Myocardial Infarction in Adulthood: a Systematic Review and Meta-analysis.


ABSTRACT: The aim of this systematic review and meta-analysis was to estimate the relationship between cumulative adverse childhood experiences (ACEs) and myocardial infarction (MI) in adulthood and to examine the role of potential confounding factors that may have contributed to the association. Studies examining the association of cumulative ACEs with MI among adults were identified by searching PubMed/MEDLINE, PsycINFO, ScienceDirect, and ProQuest Dissertations and Thesis. Individual estimates of odds ratios were pooled using random effects meta-analysis. Articles were pooled separately according to whether findings were adjusted for sociodemographic factors, cardiovascular disease (CVD) risk factors, and psychological factors. Several moderators were also examined: age, gender, race/ethnicity, t

SUBMITTER: Jacquet-Smailovic M 

PROVIDER: S-EPMC9360358 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature