Impact on capsule formation for three different types of implant surface tomography.

ABSTRACT: Although capsular contracture remains one of the major problems following silicone breast implantation, the associated mechanism has yet to be determined. This study thus aimed to investigate capsule formation and capsular contracture using three types of implants with different surface topographies in vivo. Three types of implants (i.e., smooth, macrotexture, and nanotexture) with different surface topographies were inserted in a total of 48 Wistar rats. After 4 and 12 weeks, the samples were analyzed via histological, immunohistochemical, and Western blot examination. To identify implant movement, the degree to which implant position changed was measured. And the surface topography was characterized using scanning electron microscopy. Hematoxylin-eosin staining showed that the nanotextur

SUBMITTER: Jeon HJ 

PROVIDER: S-EPMC9360403 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature