Subsequent Primary Cancer Risk Among 5-Year Survivors of Adolescent and Young Adult Cancers.

ABSTRACT:

Background

A comprehensive examination of the incidence and mortality of subsequent primary cancers (SPCs) among adolescent and young adult (AYA) cancer survivors in the United States is lacking.

Methods

Cancer incidence and mortality among 170 404 cancer survivors of 5 or more years who were aged 15-39 years at first primary cancer diagnosis during 1975-2013 in 9 Surveillance, Epidemiology, and End Results registries were compared with those in the general population using standardized incidence ratio (SIR), absolute excess incidence (AEI), standardized mortality ratio (SMR), and absolute excess mortality (AEM).

Results

During a mean follow-up of 14.6 years, 13 420 SPC cases and 5008 SPC deaths occurred among survivors (excluding the same site as index cancer), corre

SUBMITTER: Sung H 

PROVIDER: S-EPMC9360462 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature