Κey Role of Early Source Control in Candidemic Patients With Sepsis or Septic Shock.

ABSTRACT:

Background

Despite advances in diagnostic and therapeutic approaches, candidemia remains associated with high mortality rates. This study aimed at identifying predictors of mortality among patients with candidemia, with a focus on early interventions that can improve prognosis.

Methods

This was a single-center retrospective study including all adult patients with at least 1 positive blood culture for Candida species from 2014 to 2021.

Results

A total of 222 episodes of candidemia were included. Most candidemias were of unknown origin (36%) or vascular catheter related (29%). Septic shock developed in 29% episodes. Overall, 14-day mortality rate was 23%. In univariate analyses, septic shock was associated with higher 14-day mortality, whereas catheter-related ca

SUBMITTER: Papadimitriou-Olivgeris M 

PROVIDER: S-EPMC9361172 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature